Tuesday, January 29, 2008

Landau-Kleffner Syndrome

I was looking up unique and fairly unknown syndromes as research for the group project when I came across this puzzling, yet intriguing neurological syndrome called Landau-Kleffner syndrome (LKS). Wikipedia says , " [it] is a rare, childhood... syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language)..."

What is interesting is that a child develops normally but somewhere between the ages of 5 and 7 they loose the language skills they've learned. Many also suffer from seizures. Because it is so rare and seemingly hard to pinpoint, it is often misdiagnosed as autism, pervasive developmental disorder, hearing impairment, learning disability, auditory/verbal processing disorder, ADD, mental retardation, childhood schizophrenia, or emotional/behavioral problems.

LKS is treatable with a combination of medications (i.e. anticonvulsants) and speech therapy which is started as early as the issue is recognized. There is also a controversial treatment which involves surgery. It's known as multiple subpial transection and what happens is that multiple incisions are made through the cortex of the affected part of the brain, severing the axonal tracts in the subjacent white matter.

Some affected children may have a permanent severe language disorder, while others may regain much of their language abilities (but it may take months or years). In some instances, remission and relapse can occur. The prognosis is improved when the onset of the disorder is after age 6 and when speech therapy is started early. Seizures generally disappear by adulthood.

Pretty crazy, huh? Who would have thought such a thing could happen. It truly is an example of just how complex our minds are.

5 comments:

JAKE said...

Nobody has yet commented you and I felt bad. Poor soul.

Anyway, yes, truly amazing. We probably will never understand every part of our mind, but we're getting there. We came a long way. At least I think we did.

Amanda said...

Wow, that's interesting. It's odd that these diseases come up and not a lot of people know about them. What is the point of being a doctor if you don't know everything that's out there. Just because it's rare, doesn't mean that people won't develop it. Scary to think that things we take for granted, like our own minds, can get taken away from us so easily.

RWinkel said...

Jesse, could you come up with a few more academic resources on the syndrome? Google scholar is always a good start...

ssun said...

As I'm reading this interesting post, I got curious about how do doctors or therapists determine whether this young child has ADD or autism or LKD syndrome since the symtoms of these kind of mental deseases have many simularities and no physical evidence? Are they always 100% sure of their decisions?

certified"BITCHES"2008 (its our year) said...

Reading this article makes me realize how much power we give to doctors. We treat them as if they are gods. If a doctor says your something then by all means its time to alienate a person by a classification. could we imagine if we had a senate of doctors running the country